PRECLINICAL AND EARLY CLINICAL DEVELOPMENT OF TENOFOVIR ALAFENAMIDE/ELVITEGRAVIR TOPICAL INSERTS FOR EFFECTIVE ON-DEMAND VAGINAL AND RECTAL HIV PREVENTION

HIV/AIDS remains a global public health issue, and products available for the prevention of HIV infections are limited, especially those for short-acting, on-demand, user-controlled applications.Topical inserts are products that can be applied vaginally or rectally and have been explored as drug delivery systems.To fill the gap in the HIV preventio

Safe and humane transportation of live animals requires dedicated, informed personnel who carefully plan and attend to the details of appropriate animal care and handling throughout the shipping process.Specifically, although transportation of non-human primates shares goals common to all live animal transport, it also poses ART unique challenges s

Pediatric subtrochanteric fractures Whips-Quirts have been treated historically with intramedullary nailing, sliding hip screw, or pediatric proximal femoral locking plates, which are often based on the fracture pattern or availability of suitable implants.It is desirable to use a technique of fixation that will not only restore the hip biomechanic

In 2015, the EU Educational Policy document “Science Education for Responsible Citizenship” introduced the concept of Open Schooling as a promising approach to transform schools into innovation hubs within their local communities.In an open school environment, external ideas need to challenge traditional internal views and, in turn, to benefit